Efficient targeted mutagenesis in the monarch butterfly using zinc-finger nucleases

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Efficient targeted mutagenesis in the monarch butterfly using zinc-finger nucleases.

The development of reverse-genetic tools in "nonmodel" insect species with distinct biology is critical to establish them as viable model systems. The eastern North American monarch butterfly (Danaus plexippus), whose genome is sequenced, has emerged as a model to study animal clocks, navigational mechanisms, and the genetic basis of long-distance migration. Here, we developed a highly efficien...

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ژورنال

عنوان ژورنال: Genome Research

سال: 2012

ISSN: 1088-9051

DOI: 10.1101/gr.145599.112